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Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

Cancer is the leading cause of death in the geriatric dog population. Currently, the use of immune checkpoint inhibitors (ICIs) such as anti-CTLA4 antibodies has markedly improved the prognosis of several cancers in their advanced stages. However, ICIs targeting CTLA4 blockade to treat canine cancer...

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Detalles Bibliográficos
Autores principales:	Marable, Jonathan, Ruiz, Damien, Jaiswal, Anil K., Bhattacharya, Ritankar, Pantazes, Robert, Agarwal, Payal, Suryawanshi, Amol S., Bedi, Deepa, Mishra, Amarjit, Smith, Bruce F., Sandey, Maninder
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531395/ https://www.ncbi.nlm.nih.gov/pubmed/34675296 http://dx.doi.org/10.1038/s41598-021-00325-3

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