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Delta-Like Protein 3 Expression in Paired Chemonaive and Chemorelapsed Small Cell Lung Cancer Samples

Rovalpituzumab tesirine (Rova-T), an antibody-drug conjugate directed against Delta-like protein 3 (DLL3), is under development for patients with small cell lung cancer (SCLC). DLL3 is expressed on the majority of SCLC samples. Because SCLC is rarely biopsied in the course of disease, data regarding...

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Detalles Bibliográficos
Autores principales: Kuempers, Christiane, Jagomast, Tobias, Krupar, Rosemarie, Paulsen, Finn-Ole, Heidel, Carsten, Ribbat-Idel, Julika, Idel, Christian, Märkl, Bruno, Anlauf, Martin, Berezowska, Sabina, Tiemann, Markus, Bösmüller, Hans, Fend, Falko, Kalsdorf, Barbara, Bohnet, Sabine, Dreyer, Eva, Sailer, Verena, Kirfel, Jutta, Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531433/
https://www.ncbi.nlm.nih.gov/pubmed/34692726
http://dx.doi.org/10.3389/fmed.2021.734901