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Lentiviral and adeno-associated vectors efficiently transduce mouse T lymphocytes when targeted to murine CD8

Preclinical studies on gene delivery into mouse lymphocytes are often hampered by insufficient activity of lentiviral (LV) and adeno-associated vectors (AAVs) as well as missing tools for cell type selectivity when considering in vivo gene therapy. Here, we selected designed ankyrin repeat proteins...

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Detalles Bibliográficos
Autores principales: Michels, Alexander, Frank, Annika M., Günther, Dorothee M., Mataei, Mehryad, Börner, Kathleen, Grimm, Dirk, Hartmann, Jessica, Buchholz, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531454/
https://www.ncbi.nlm.nih.gov/pubmed/34729380
http://dx.doi.org/10.1016/j.omtm.2021.09.014