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CD200 Blockade Modulates Tumor Immune Microenvironment but Fails to Show Efficacy in Inhibiting Tumor Growth in a Murine Model of Melanoma

CD200-CD200R pathway regulates immune responses and has been implicated in the pathogenesis of a number of cancer types. CD200 blockade is considered a strategy for immunotherapy of CD200-positive cancers such as melanoma. Thus, it is critical to understand the potential impacts of CD200 blockade in...

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Detalles Bibliográficos
Autores principales: Talebian, Fatemeh, Yu, Jianyu, Lynch, Kimberly, Liu, Jin-Qing, Carson, William E., Bai, Xue-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531493/
https://www.ncbi.nlm.nih.gov/pubmed/34692697
http://dx.doi.org/10.3389/fcell.2021.739816