Trimetazidine Modulates Mitochondrial Redox Status and Disrupted Glutamate Homeostasis in a Rat Model of Epilepsy

Mitochondrial oxidative status exerts an important role in modulating glia–neuron interplay during epileptogenesis. Trimetazidine (TMZ), a well-known anti-ischemic drug, has shown promising potential against a wide range of neurodegenerative disorders including epilepsy. Nevertheless, the exact mech...

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Detalles Bibliográficos
Autores principales: Al-Shorbagy, Muhammad Y., Wadie, Walaa, El-Tanbouly, Dalia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531497/
https://www.ncbi.nlm.nih.gov/pubmed/34690772
http://dx.doi.org/10.3389/fphar.2021.735165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531497/
https://www.ncbi.nlm.nih.gov/pubmed/34690772
http://dx.doi.org/10.3389/fphar.2021.735165

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