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Metabolic Engineering of Enterobacter aerogenes for Improved 2,3-Butanediol Production by Manipulating NADH Levels and Overexpressing the Small RNA RyhB

Biotechnological production of 2,3-butanediol (2,3-BD), a versatile platform bio-chemical and a potential biofuel, is limited due to by-product toxicity. In this study, we aimed to redirect the metabolic flux toward 2,3-BD in Enterobacter aerogenes (E. aerogenes) by increasing the intracellular NADH...

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Detalles Bibliográficos
Autores principales: Wu, Yan, Chu, Wanying, Yang, Jiayao, Xu, Yudong, Shen, Qi, Yang, Haoning, Xu, Fangxu, Liu, Yefei, Lu, Ping, Jiang, Ke, Zhao, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531500/
https://www.ncbi.nlm.nih.gov/pubmed/34691005
http://dx.doi.org/10.3389/fmicb.2021.754306