Variations in the SDN Loop of Class A Beta-Lactamases: A Study of the Molecular Mechanism of BlaC (Mycobacterium tuberculosis) to Alter the Stability and Catalytic Activity Towards Antibiotic Resistance of MBIs

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis calls for an immediate search for novel treatment strategies. Recently, BlaC, the principal beta-lactamase of Mycobacterium tuberculosis, was recognized as a potential therapeutic target. BlaC belongs to Amb...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Sourya, Junghare, Vivek, Pandey, Niteesh Kumar, Baidya, Subhecchha, Agarwal, Harsha, Das, Neeladrisingha, Banerjee, Ayan, Ghosh, Debashish, Roy, Partha, Patra, Hirak K., Hazra, Saugata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531524/
https://www.ncbi.nlm.nih.gov/pubmed/34690953
http://dx.doi.org/10.3389/fmicb.2021.710291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531524/
https://www.ncbi.nlm.nih.gov/pubmed/34690953
http://dx.doi.org/10.3389/fmicb.2021.710291

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