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Enriched transcriptome analysis of laser capture microdissected populations of single cells to investigate intracellular heterogeneity in immunostained FFPE sections

To investigate intracellular heterogeneity, cell capture of particular cell populations followed by transcriptome analysis has been highly effective in freshly isolated tissues. However, this approach has been quite challenging in immunostained formalin-fixed paraffin-embedded (FFPE) sections. This...

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Detalles Bibliográficos
Autores principales: Hammoudeh, Sarah M., Hammoudeh, Arabella M., Venkatachalam, Thenmozhi, Rawat, Surendra, Jayakumar, Manju N., Rahmani, Mohamed, Hamoudi, Rifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531757/
https://www.ncbi.nlm.nih.gov/pubmed/34745451
http://dx.doi.org/10.1016/j.csbj.2021.09.010