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Comparison of the Efficacy and Safety of Different Doses of Linaclotide for Patients with Chronic Constipation: A Meta-Analysis and Bayesian Analysis

BACKGROUND: It is ambiguous whether a higher dose of linaclotide provides higher efficacy for chronic constipation (CC) patients. The meta-analysis aimed to assess the efficacy and safety of linaclotide doses ranging from 62.5 μg to 600 μg for CC patients. METHODS: A comprehensive search was conduct...

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Detalles Bibliográficos
Autores principales: Yang, Jiao, Lei, YanChang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531776/
https://www.ncbi.nlm.nih.gov/pubmed/34691232
http://dx.doi.org/10.1155/2021/9923879