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Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization

Oxidative stress and inflammatory response are closely related to nephrolithiasis. This study is aimed at exploring whether rosiglitazone (ROSI), a regulator of macrophage (Mp) polarization, could reduce renal calcium oxalate (CaOx) deposition by ameliorating oxidative stress and inflammatory respon...

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Detalles Bibliográficos
Autores principales: Lu, Hongyan, Sun, Xifeng, Jia, Min, Sun, Fa, Zhu, Jianguo, Chen, Xiaolong, Chen, Kun, Jiang, Kehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531781/
https://www.ncbi.nlm.nih.gov/pubmed/34691355
http://dx.doi.org/10.1155/2021/5527137