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CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease

Leptomeningeal disease (LMD) in melanoma patients is associated with significant neurological sequela and has a dismal outcome, with survival measured typically in weeks. Despite the therapeutic benefit of targeted therapies and immunotherapies for Stage IV melanoma, patients with LMD do not typical...

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Detalles Bibliográficos
Autores principales: Najem, Hinda, Marisetty, Anantha, Horbinski, Craig, Long, James, Huse, Jason T., Glitza Oliva, Isabella C., Ferguson, Sherise D., Kumthekar, Priya U., Wainwright, Derek A., Chen, Peiwen, Lesniak, Maciej S., Burks, Jared K., Heimberger, Amy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531809/
https://www.ncbi.nlm.nih.gov/pubmed/34691054
http://dx.doi.org/10.3389/fimmu.2021.745893