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CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease
Leptomeningeal disease (LMD) in melanoma patients is associated with significant neurological sequela and has a dismal outcome, with survival measured typically in weeks. Despite the therapeutic benefit of targeted therapies and immunotherapies for Stage IV melanoma, patients with LMD do not typical...
Autores principales: | Najem, Hinda, Marisetty, Anantha, Horbinski, Craig, Long, James, Huse, Jason T., Glitza Oliva, Isabella C., Ferguson, Sherise D., Kumthekar, Priya U., Wainwright, Derek A., Chen, Peiwen, Lesniak, Maciej S., Burks, Jared K., Heimberger, Amy B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531809/ https://www.ncbi.nlm.nih.gov/pubmed/34691054 http://dx.doi.org/10.3389/fimmu.2021.745893 |
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