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FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway

Osteoarthritis (OA) is a common degenerative disease that can lead to severe joint pain and loss of function, seriously threatening the health and normal life of patients. At present, the pathogenesis of OA remains to be clarified. Recent studies have shown that fatty acid-binding protein 4 (FABP4)...

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Detalles Bibliográficos
Autores principales: Mao, Huajie, Han, Bin, Li, Hao, Tao, Yiqing, Wu, Weigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532115/
https://www.ncbi.nlm.nih.gov/pubmed/34651666
http://dx.doi.org/10.3892/mmr.2021.12495