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Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments

[Image: see text] Dynamic covalent chemistry (DCvC) has emerged as a versatile synthetic tool for devising stable, stimuli-responsive linkers or conjugates. The interplay of binding affinity, association and dissociation constants exhibits a strong influence on the selectivity of the reaction, the c...

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Detalles Bibliográficos
Autores principales: Zegota, Maksymilian Marek, Müller, Michael Andreas, Lantzberg, Bellinda, Kizilsavas, Gönül, Coelho, Jaime A. S., Moscariello, Pierpaolo, Martínez-Negro, María, Morsbach, Svenja, Gois, Pedro M. P., Wagner, Manfred, Ng, David Y. W., Kuan, Seah Ling, Weil, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532147/
https://www.ncbi.nlm.nih.gov/pubmed/34632780
http://dx.doi.org/10.1021/jacs.1c06559