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Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments
[Image: see text] Dynamic covalent chemistry (DCvC) has emerged as a versatile synthetic tool for devising stable, stimuli-responsive linkers or conjugates. The interplay of binding affinity, association and dissociation constants exhibits a strong influence on the selectivity of the reaction, the c...
Autores principales: | Zegota, Maksymilian Marek, Müller, Michael Andreas, Lantzberg, Bellinda, Kizilsavas, Gönül, Coelho, Jaime A. S., Moscariello, Pierpaolo, Martínez-Negro, María, Morsbach, Svenja, Gois, Pedro M. P., Wagner, Manfred, Ng, David Y. W., Kuan, Seah Ling, Weil, Tanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532147/ https://www.ncbi.nlm.nih.gov/pubmed/34632780 http://dx.doi.org/10.1021/jacs.1c06559 |
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