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The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies

The extracellular matrix (ECM) of the cerebral vasculature provides a pathway for the flow of interstitial fluid (ISF) and solutes out of the brain by intramural periarterial drainage (IPAD). Failure of IPAD leads to protein elimination failure arteriopathies such as cerebral amyloid angiopathy (CAA...

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Detalles Bibliográficos
Autores principales: Sharp, Matthew MacGregor, Cassidy, Jordan, Thornton, Thomas, Lyles, James, Keable, Abby, Gatherer, Maureen, Yasui, Masato, Abe, Yoichiro, Shibata, Shinsuke, Weller, Roy O., Górecki, Dariusz C., Carare, Roxana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532274/
https://www.ncbi.nlm.nih.gov/pubmed/34674769
http://dx.doi.org/10.1186/s40478-021-01274-8