Cargando…
The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies
The extracellular matrix (ECM) of the cerebral vasculature provides a pathway for the flow of interstitial fluid (ISF) and solutes out of the brain by intramural periarterial drainage (IPAD). Failure of IPAD leads to protein elimination failure arteriopathies such as cerebral amyloid angiopathy (CAA...
Autores principales: | Sharp, Matthew MacGregor, Cassidy, Jordan, Thornton, Thomas, Lyles, James, Keable, Abby, Gatherer, Maureen, Yasui, Masato, Abe, Yoichiro, Shibata, Shinsuke, Weller, Roy O., Górecki, Dariusz C., Carare, Roxana O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532274/ https://www.ncbi.nlm.nih.gov/pubmed/34674769 http://dx.doi.org/10.1186/s40478-021-01274-8 |
Ejemplares similares
-
α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression
por: Hawkes, Cheryl A., et al.
Publicado: (2022) -
ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes
por: Keable, Abby, et al.
Publicado: (2020) -
Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia
por: MacGregor Sharp, Matthew, et al.
Publicado: (2020) -
Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease
por: Frost, Miles, et al.
Publicado: (2020) -
Dystrophins and dystrobrevins
por: Roberts, Roland G
Publicado: (2001)