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Induced pluripotent stem cells can improve thrombolytic effect of low-dose rt-PA after acute carotid thrombosis in rat

BACKGROUND: Intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is the standard treatment for acute ischemic stroke. Standard-dose rt-PA (0.9 mg/kg) is known to achieve good recanalization but carries a high bleeding risk. Lower dose of rt-PA has less bleeding risk but ca...

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Detalles Bibliográficos
Autores principales: Hsieh, Hsi-Lung, Liang, Ching-Chung, Lu, Cheng-You, Yang, Jen-Tsung, Chung, Chiu-Yen, Ko, Yu-Shien, Lee, Tsong-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532293/
https://www.ncbi.nlm.nih.gov/pubmed/34674761
http://dx.doi.org/10.1186/s13287-021-02615-z