A small molecule modulating monounsaturated fatty acids and Wnt signaling confers maintenance to induced pluripotent stem cells against endodermal differentiation

BACKGROUND: Stearoyl-coenzyme A desaturase 1 (SCD1) is required for de novo synthesis of fatty acids. Through the fatty acid acylation process, this enzyme orchestrates post-translational modifications to proteins involved in cell development and differentiation. In this study, we used biochemical m...

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Detalles Bibliográficos
Autores principales: Hosseini, Vahid, Kalantary-Charvadeh, Ashkan, Hajikarami, Maryam, Fayyazpour, Parisa, Rahbarghazi, Reza, Totonchi, Mehdi, Darabi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532309/
https://www.ncbi.nlm.nih.gov/pubmed/34674740
http://dx.doi.org/10.1186/s13287-021-02617-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532309/
https://www.ncbi.nlm.nih.gov/pubmed/34674740
http://dx.doi.org/10.1186/s13287-021-02617-x

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