Cargando…

A small molecule modulating monounsaturated fatty acids and Wnt signaling confers maintenance to induced pluripotent stem cells against endodermal differentiation

BACKGROUND: Stearoyl-coenzyme A desaturase 1 (SCD1) is required for de novo synthesis of fatty acids. Through the fatty acid acylation process, this enzyme orchestrates post-translational modifications to proteins involved in cell development and differentiation. In this study, we used biochemical m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hosseini, Vahid, Kalantary-Charvadeh, Ashkan, Hajikarami, Maryam, Fayyazpour, Parisa, Rahbarghazi, Reza, Totonchi, Mehdi, Darabi, Masoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532309/ https://www.ncbi.nlm.nih.gov/pubmed/34674740 http://dx.doi.org/10.1186/s13287-021-02617-x

Ejemplares similares

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
por: Athanasouli, Paraskevi, et al.
Publicado: (2023)

Current progress in hepatic tissue regeneration by tissue engineering
por: Hosseini, Vahid, et al.
Publicado: (2019)

High-Dimensional Design-Of-Experiments Extracts Small-Molecule-Only Induction Conditions for Dorsal Pancreatic Endoderm from Pluripotency
por: Bukys, Michael A., et al.
Publicado: (2020)

Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm
por: Okubo, Tadashi, et al.
Publicado: (2004)

GATA6 is essential for endoderm formation from human pluripotent stem cells
por: Fisher, J. B., et al.
Publicado: (2017)

Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells
por: Lv, Jing, et al.
Publicado: (2022)

Differentiation of Definitive Endoderm from Human Induced Pluripotent Stem Cells on hMSCs Feeder in a Defined Medium
por: Jaafarpour, Zahra, et al.
Publicado: (2016)

Autophagy modulation altered differentiation capacity of CD146(+) cells toward endothelial cells, pericytes, and cardiomyocytes
por: Hassanpour, Mehdi, et al.
Publicado: (2020)

Wnt and Hedgehog Signaling Regulate the Differentiation of F9 Cells into Extraembryonic Endoderm
por: Deol, Gurjoth S. J., et al.
Publicado: (2017)

Monounsaturated Fatty Acids in Obesity-Related Inflammation
por: Ravaut, Gaetan, et al.
Publicado: (2020)

PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines
por: Lin, Jiangwei, et al.
Publicado: (2017)

Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review
por: Fayezi, Shabnam, et al.
Publicado: (2022)

OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells
por: Parenti, Anthony, et al.
Publicado: (2016)

Generation of human liver organoids from pluripotent stem cell-derived hepatic endoderms
por: Kulkeaw, Kasem, et al.
Publicado: (2020)

Kinetics of Saturated, Monounsaturated, and Polyunsaturated Fatty Acids in Humans
por: Nelson, Robert H., et al.
Publicado: (2013)

Plasma Saturated and Monounsaturated Fatty Acids in Behçet’s Disease
por: Messedi, Meriam, et al.
Publicado: (2018)

Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm
por: Sun-Wada, Ge-Hong, et al.
Publicado: (2021)

Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture
por: Takeuchi, Hiroki, et al.
Publicado: (2014)

Characterisation of human induced pluripotent stem cell-derived hepatocyte-like cells and endodermal progenitors
por: Matz, Peggy, et al.
Publicado: (2014)

Secreted Cerberus1 as a Marker for Quantification of Definitive Endoderm Differentiation of the Pluripotent Stem Cells
por: Iwashita, Hidefumi, et al.
Publicado: (2013)

Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells
por: Wamaitha, Sissy E., et al.
Publicado: (2015)

Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines
por: Siller, Richard, et al.
Publicado: (2016)

Suppression of ERK signalling abolishes primitive endoderm formation but does not promote pluripotency in rabbit embryo
por: Piliszek, Anna, et al.
Publicado: (2017)

Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells
por: Bilz, Nicole C., et al.
Publicado: (2019)

Modeling endodermal organ development and diseases using human pluripotent stem cell-derived organoids
por: Pan, Fong Cheng, et al.
Publicado: (2020)

A dataset of definitive endoderm and hepatocyte differentiations from human induced pluripotent stem cells
por: Tanaka, Yuki, et al.
Publicado: (2023)

Tangeretin protects renal tubular epithelial cells against experimental cisplatin toxicity
por: Nazari Soltan Ahmad, Saeed, et al.
Publicado: (2019)

WNT3 Is a Biomarker Capable of Predicting the Definitive Endoderm Differentiation Potential of hESCs
por: Jiang, Wei, et al.
Publicado: (2013)

Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells
por: Kishimoto, Keishi, et al.
Publicado: (2020)

In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm
por: Novakovsky, Gherman, et al.
Publicado: (2023)

A System to Enrich for Primitive Streak-Derivatives, Definitive Endoderm and Mesoderm, from Pluripotent Cells in Culture
por: Vassilieva, Svetlana, et al.
Publicado: (2012)

Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
por: Butcher, Lee M., et al.
Publicado: (2016)

Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells
por: Allison, Thomas F., et al.
Publicado: (2018)

GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm
por: Meng, Yue, et al.
Publicado: (2018)

Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation
por: Li, Qing V., et al.
Publicado: (2019)

Human Pluripotent Stem Cell-Derived Micropatterned Ectoderm Allows Cell Sorting of Meso-Endoderm Lineages
por: Yang, Yang, et al.
Publicado: (2022)

Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells
por: Montané-Romero, Martha E., et al.
Publicado: (2023)

Dietary Monounsaturated Fatty Acids Intake and Risk of Skin Photoaging
por: Latreille, Julie, et al.
Publicado: (2012)

Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum
por: Teo, Adrian Kee Keong, et al.
Publicado: (2014)

A high-content small molecule screen identifies novel inducers of definitive endoderm
por: Korostylev, Alexander, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0nc1n5grant04u8f528rbdnrok