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Primary high-grade serous ovarian cancer cells are sensitive to senescence induced by carboplatin and paclitaxel in vitro

BACKGROUND: Various types of normal and cancer cells undergo senescence in response to carboplatin and paclitaxel, which are considered the gold standard treatments in ovarian cancer management. Surprisingly, the effect of these drugs on ovarian cancer cell senescence remained unknown. METHODS: The...

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Detalles Bibliográficos
Autores principales: Uruski, Paweł, Sepetowska, Agnieszka, Konieczna, Corinna, Pakuła, Martyna, Wyrwa, Michał, Tussupkaliyev, Akylbek, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532320/
https://www.ncbi.nlm.nih.gov/pubmed/34674640
http://dx.doi.org/10.1186/s11658-021-00287-4