Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence

BACKGROUND: Application of mesenchymal stem cell-derived exosomes (MSC-EXO) has emerged as a novel therapeutic strategy for myocardial infarction (MI). Our previous study showed that pretreatment with hemin, a potent heme oxygenase-1 (HO-1) inducer, enhanced the cardioprotective effects of MSCs in a...

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Detalles Bibliográficos
Autores principales: Zheng, Huifeng, Liang, Xiaoting, Han, Qian, Shao, Zhuang, Zhang, Yuxiao, Shi, Linli, Hong, Yimei, Li, Weifeng, Mai, Cong, Mo, Qingwen, Fu, Qingling, Ma, Xiaoxue, Lin, Fang, Li, Mimi, Hu, Bei, Li, Xin, Zhang, Yuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532335/
https://www.ncbi.nlm.nih.gov/pubmed/34674708
http://dx.doi.org/10.1186/s12951-021-01077-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532335/
https://www.ncbi.nlm.nih.gov/pubmed/34674708
http://dx.doi.org/10.1186/s12951-021-01077-y

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