Drug target inference by mining transcriptional data using a novel graph convolutional network framework

A fundamental challenge that arises in biomedicine is the need to characterize compounds in a relevant cellular context in order to reveal potential on-target or off-target effects. Recently, the fast accumulation of gene transcriptional profiling data provides us an unprecedented opportunity to exp...

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Detalles Bibliográficos
Autores principales: Zhong, Feisheng, Wu, Xiaolong, Yang, Ruirui, Li, Xutong, Wang, Dingyan, Fu, Zunyun, Liu, Xiaohong, Wan, XiaoZhe, Yang, Tianbiao, Fan, Zisheng, Zhang, Yinghui, Luo, Xiaomin, Chen, Kaixian, Zhang, Sulin, Jiang, Hualiang, Zheng, Mingyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532448/
https://www.ncbi.nlm.nih.gov/pubmed/34677780
http://dx.doi.org/10.1007/s13238-021-00885-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532448/
https://www.ncbi.nlm.nih.gov/pubmed/34677780
http://dx.doi.org/10.1007/s13238-021-00885-0

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