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Salicylate Induced GABA(A)R Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons

BACKGROUND: Sodium salicylate (SS) induces excitotoxicity of spiral ganglion neurons (SGNs) by inhibiting the response of γ-aminobutyric acid type A receptors (GABA(A)Rs). Our previous studies have shown that SS can increase the internalization of GABA(A)Rs on SGNs, which involves dopamine D1-like r...

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Detalles Bibliográficos
Autores principales: Qin, Jiangyuan, Wei, Tingjia, Chen, Huiying, Lin, Xiaoyu, Qin, Danxue, Wei, Fangyu, Liu, Peiqiang, Ye, Wenhua, Su, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532520/
https://www.ncbi.nlm.nih.gov/pubmed/34657931
http://dx.doi.org/10.12659/MSM.933278