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Beta-Lactams Dosing in Critically Ill Patients with Gram-Negative Bacterial Infections: A PK/PD Approach

Beta-lactam antibiotics are often the backbone of treatment for Gram-negative infections in the critically ill. Beta-lactams exhibit time-dependent killing, and their efficacy depends on the percentage of dosing interval that the concentration remains above the minimum inhibitory concentration. The...

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Detalles Bibliográficos
Autores principales: Maguigan, Kelly L., Al-Shaer, Mohammad H., Peloquin, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532626/
https://www.ncbi.nlm.nih.gov/pubmed/34680734
http://dx.doi.org/10.3390/antibiotics10101154