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High-Level Carbapenem Resistance among OXA-48-Producing Klebsiella pneumoniae with Functional OmpK36 Alterations: Maintenance of Ceftazidime/Avibactam Susceptibility

The aim of this work was to analyze outer membrane porin-encoding genes (ompK35 and ompK36) in a collection of OXA-48 producing Klebsiella pneumoniae, to assess the effect of porin alterations on the susceptibility to ceftazidime/avibactam, and to describe a screening methodology for phenotypic dete...

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Detalles Bibliográficos
Autores principales: Lumbreras-Iglesias, Pilar, Rodicio, María Rosario, Valledor, Pablo, Suárez-Zarracina, Tomás, Fernández, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532661/
https://www.ncbi.nlm.nih.gov/pubmed/34680754
http://dx.doi.org/10.3390/antibiotics10101174