Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence

Antibiotic-resistant Pseudomonas aeruginosa infections are the primary cause of mortality in people with cystic fibrosis (CF). Yet, it has only recently become appreciated that resistance mutations can also increase P. aeruginosa virulence, even in the absence of antibiotics. Moreover, the mechanism...

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Detalles Bibliográficos
Autores principales: Vaillancourt, Mylene, Limsuwannarot, Sam P., Bresee, Catherine, Poopalarajah, Rahgavi, Jorth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532662/
https://www.ncbi.nlm.nih.gov/pubmed/34680745
http://dx.doi.org/10.3390/antibiotics10101164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532662/
https://www.ncbi.nlm.nih.gov/pubmed/34680745
http://dx.doi.org/10.3390/antibiotics10101164

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