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In Vivo Pharmacodynamics of β-Lactams/Nacubactam against Carbapenem-Resistant and/or Carbapenemase-Producing Enterobacter cloacae and Klebsiella pneumoniae in Murine Pneumonia Model

Carbapenem-resistant Enterobacterales (CRE) and carbapenemase-producing Enterobacterales (CPE) have become global threats. CRE− and CPE− derived infections have been associated with high mortality due to limited treatment options. Nacubactam is a β-lactamase inhibitor and belongs to the new class of...

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Detalles Bibliográficos
Autores principales: Hagihara, Mao, Kato, Hideo, Sugano, Toshie, Okade, Hayato, Sato, Nobuo, Shibata, Yuichi, Sakanashi, Daisuke, Hirai, Jun, Asai, Nobuhiro, Suematsu, Hiroyuki, Yamagishi, Yuka, Mikamo, Hiroshige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532682/
https://www.ncbi.nlm.nih.gov/pubmed/34680760
http://dx.doi.org/10.3390/antibiotics10101179