Kinase Inhibitor Library Screening Identifies the Cancer Therapeutic Sorafenib and Structurally Similar Compounds as Strong Inhibitors of the Fungal Pathogen Histoplasma capsulatum

Histoplasma capsulatum is a dimorphic fungal pathogen endemic to the midwestern and southern United States. It causes mycoses ranging from subclinical respiratory infections to severe systemic disease, and is of particular concern for immunocompromised patients in endemic areas. Clinical management...

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Detalles Bibliográficos
Autores principales: Berkes, Charlotte, Franco, Jimmy, Lawson, Maxx, Brann, Katelynn, Mermelstein, Jessica, Laverty, Daniel, Connors, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532743/
https://www.ncbi.nlm.nih.gov/pubmed/34680804
http://dx.doi.org/10.3390/antibiotics10101223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532743/
https://www.ncbi.nlm.nih.gov/pubmed/34680804
http://dx.doi.org/10.3390/antibiotics10101223

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