Cystine and Methionine Deficiency Promotes Ferroptosis by Inducing B-Cell Translocation Gene 1

Ferroptosis is a type of programmed necrosis triggered by iron-dependent lipid peroxidation. We investigated the role of B-cell translocation gene 1 (BTG1) in cystine and methionine deficiency (CST/Met (−))-mediated cell death. CST/Met (−) depleted reduced and oxidized glutathione in hepatocyte-deri...

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Detalles Bibliográficos
Autores principales: Cho, Il-Je, Kim, Doyeon, Kim, Eun-Ok, Jegal, Kyung-Hwan, Kim, Jae-Kwang, Park, Sang-Mi, Zhao, Rongjie, Ki, Sung-Hwan, Kim, Sang-Chan, Ku, Sae-Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532826/
https://www.ncbi.nlm.nih.gov/pubmed/34679678
http://dx.doi.org/10.3390/antiox10101543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532826/
https://www.ncbi.nlm.nih.gov/pubmed/34679678
http://dx.doi.org/10.3390/antiox10101543

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