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Lipid Profiles of RAS Nanoclusters Regulate RAS Function

The lipid-anchored RAS (Rat sarcoma) small GTPases (guanosine triphosphate hydrolases) are highly prevalent in human cancer. Traditional strategies of targeting the enzymatic activities of RAS have been shown to be difficult. Alternatively, RAS function and pathology are mostly restricted to nanoclu...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Hancock, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533076/
https://www.ncbi.nlm.nih.gov/pubmed/34680072
http://dx.doi.org/10.3390/biom11101439