Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes

Crosstalk between synovial fibroblasts (SF) and immune cells plays a central role in the development of rheumatoid arthritis (RA). Janus kinase inhibitors (JAKi) have proven efficacy in the treatment of RA, although clinical responses are heterogeneous. Currently, little is known regarding how JAKi...

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Detalles Bibliográficos
Autores principales: Yao, Nina, Tretter, Theresa, Kvacskay, Peter, Merkt, Wolfgang, Blank, Norbert, Lorenz, Hanns-Martin, Tykocinski, Lars-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533088/
https://www.ncbi.nlm.nih.gov/pubmed/34680530
http://dx.doi.org/10.3390/biomedicines9101413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533088/
https://www.ncbi.nlm.nih.gov/pubmed/34680530
http://dx.doi.org/10.3390/biomedicines9101413

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