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Structural and Functional Insights into α-Synuclein Fibril Polymorphism

Abnormal accumulation of aggregated α-synuclein (α-Syn) is seen in a variety of neurodegenerative diseases, including Parkinson’s disease (PD), multiple system atrophy (MSA), dementia with Lewy body (DLB), Parkinson’s disease dementia (PDD), and even subsets of Alzheimer’s disease (AD) showing Lewy-...

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Detalles Bibliográficos
Autores principales: Mehra, Surabhi, Gadhe, Laxmikant, Bera, Riya, Sawner, Ajay Singh, Maji, Samir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533119/
https://www.ncbi.nlm.nih.gov/pubmed/34680054
http://dx.doi.org/10.3390/biom11101419