Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1β Production in Kidney Proximal Tubule Cells

Protein bound-uremic toxins (PBUTs) are not efficiently removed by hemodialysis in chronic kidney disease (CKD) patients and their accumulation leads to various co-morbidities via cellular dysfunction, inflammation and oxidative stress. Moreover, it has been shown that increased intrarenal expressio...

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Detalles Bibliográficos
Autores principales: Mihajlovic, Milos, Krebber, Merle M., Yang, Yi, Ahmed, Sabbir, Lozovanu, Valeria, Andreeva, Daria, Verhaar, Marianne C., Masereeuw, Rosalinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533138/
https://www.ncbi.nlm.nih.gov/pubmed/34680443
http://dx.doi.org/10.3390/biomedicines9101326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533138/
https://www.ncbi.nlm.nih.gov/pubmed/34680443
http://dx.doi.org/10.3390/biomedicines9101326

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