Exploring the Leukemogenic Potential of GATA-1(S), the Shorter Isoform of GATA-1: Novel Insights into Mechanisms Hampering Respiratory Chain Complex II Activity and Limiting Oxidative Phosphorylation Efficiency

GATA-1 is a key regulator of hematopoiesis. A balanced ratio of its two isoforms, GATA-1(FL) and GATA-1(S), contributes to normal hematopoiesis, whereas aberrant expression of GATA-1(S) alters the differentiation/proliferation potential of hematopoietic precursors and represents a poor prognostic fa...

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Detalles Bibliográficos
Autores principales: Trombetti, Silvia, Sessa, Raffaele, Catapano, Rosa, Rinaldi, Laura, Lo Bianco, Alessandra, Feliciello, Antonio, Izzo, Paola, Grosso, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533167/
https://www.ncbi.nlm.nih.gov/pubmed/34679737
http://dx.doi.org/10.3390/antiox10101603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533167/
https://www.ncbi.nlm.nih.gov/pubmed/34679737
http://dx.doi.org/10.3390/antiox10101603

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