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Irradiation Mediates IFNα and CXCL9 Expression in Non-Small Cell Lung Cancer to Stimulate CD8(+) T Cells Activity and Migration toward Tumors

Irradiation-broken DNA fragments increase type I interferon and chemokines secretion in tumor cells. Since radiotherapy may augment tumor immunotherapy, we hypothesize that the chemokines increased by irradiation could recruit CD8(+) T cells to suppress tumor proliferation. This study intended to un...

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Detalles Bibliográficos
Autores principales: Cheng, Chun-Chia, Chang, Yi-Fang, Ho, Ai-Sheng, Sie, Zong-Lin, Chang, Jung-Shan, Peng, Cheng-Liang, Chang, Chun-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533192/
https://www.ncbi.nlm.nih.gov/pubmed/34680466
http://dx.doi.org/10.3390/biomedicines9101349