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Transcriptional Profiling of Tumorspheres Reveals TRPM4 as a Novel Stemness Regulator in Breast Cancer

Cancer stem cells (CSCs) have been implicated in the development of chemoresistance, tumor recurrence and metastasis in breast cancer, thus emerging as a promising target for novel therapies. To identify novel stemness regulators that could potentially be targeted in luminal ER(+) tumors, we perform...

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Detalles Bibliográficos
Autores principales: Verigos, John, Kordias, Dimitris, Papadaki, Styliani, Magklara, Angeliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533210/
https://www.ncbi.nlm.nih.gov/pubmed/34680485
http://dx.doi.org/10.3390/biomedicines9101368