Sequential Dynamics of Stearoyl-CoA Desaturase-1(SCD1)/Ligand Binding and Unbinding Mechanism: A Computational Study

Stearoyl-CoA desaturase-1 (SCD1 or delta-9 desaturase, D9D) is a key metabolic protein that modulates cellular inflammation and stress, but overactivity of SCD1 is associated with diseases, including cancer and metabolic syndrome. This transmembrane endoplasmic reticulum protein converts saturated f...

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Detalles Bibliográficos
Autores principales: Petroff, Anna B., Weir, Rebecca L., Yates, Charles R., Ng, Joseph D., Baudry, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533217/
https://www.ncbi.nlm.nih.gov/pubmed/34680068
http://dx.doi.org/10.3390/biom11101435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533217/
https://www.ncbi.nlm.nih.gov/pubmed/34680068
http://dx.doi.org/10.3390/biom11101435

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