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NK Cell-Mediated Eradication of Ovarian Cancer Cells with a Novel Chimeric Antigen Receptor Directed against CD44

Ovarian cancer is the most common cause of gynecological cancer-related death in the developed world. Disease recurrence and chemoresistance are major causes of poor survival rates in ovarian cancer patients. Ovarian cancer stem cells (CSCs) were shown to represent a source of tumor recurrence owing...

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Detalles Bibliográficos
Autores principales: Klapdor, Rüdiger, Wang, Shuo, Morgan, Michael A., Zimmermann, Katharina, Hachenberg, Jens, Büning, Hildegard, Dörk, Thilo, Hillemanns, Peter, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533227/
https://www.ncbi.nlm.nih.gov/pubmed/34680456
http://dx.doi.org/10.3390/biomedicines9101339