RICTOR Affects Melanoma Tumorigenesis and Its Resistance to Targeted Therapy

The network defined by phosphatidylinositol-3-kinase (PI3K), AKT, and mammalian target of rapamycin (mTOR) plays a major role in melanoma oncogenesis and has been implicated in BRAF inhibitor resistance. The central role of RICTOR (rapamycin-insensitive companion of mTOR) in this pathway has only re...

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Detalles Bibliográficos
Autores principales: Jebali, Ahlem, Battistella, Maxime, Lebbé, Céleste, Dumaz, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533235/
https://www.ncbi.nlm.nih.gov/pubmed/34680615
http://dx.doi.org/10.3390/biomedicines9101498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533235/
https://www.ncbi.nlm.nih.gov/pubmed/34680615
http://dx.doi.org/10.3390/biomedicines9101498

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