Hydroxychloroquine Attenuates Acute Inflammation (LPS)-Induced Apoptosis via Inhibiting TRPV1 Channel/ROS Signaling Pathways in Human Monocytes

SIMPLE SUMMARY: LPS is a well-known agent in cell line models, including U937 monocytes, for inducing acute inflammation (INF). It is not known whether antioxidant HCQ, through the inhibition of TRPV1 in U937, can decrease oxidative monocyte toxicity and cell death. We investigated the modulator act...

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Detalles Bibliográficos
Autores principales: Güzel, Mustafa, Akpınar, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533250/
https://www.ncbi.nlm.nih.gov/pubmed/34681066
http://dx.doi.org/10.3390/biology10100967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533250/
https://www.ncbi.nlm.nih.gov/pubmed/34681066
http://dx.doi.org/10.3390/biology10100967

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