Bis-thiobarbiturates as Promising Xanthine Oxidase Inhibitors: Synthesis and Biological Evaluation

Xanthine oxidase (XO) is the enzyme responsible for the conversion of endogenous purines into uric acid. Therefore, this enzyme has been associated with pathological conditions caused by hyperuricemia, such as the disease commonly known as gout. Barbiturates and their congeners thiobarbiturates repr...

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Detalles Bibliográficos
Autores principales: Serrano, João L., Lopes, Diana, Reis, Melani J. A., Boto, Renato E. F., Silvestre, Samuel, Almeida, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533253/
https://www.ncbi.nlm.nih.gov/pubmed/34680559
http://dx.doi.org/10.3390/biomedicines9101443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533253/
https://www.ncbi.nlm.nih.gov/pubmed/34680559
http://dx.doi.org/10.3390/biomedicines9101443

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