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Platelet-Derived Growth Factor Induces SASP-Associated Gene Expression in Human Multipotent Mesenchymal Stromal Cells but Does Not Promote Cell Senescence

Activation of multipotent mesenchymal stromal cells (MSCs) is a central part of tissue response to damage. Platelet-derived growth factor (PDGF-BB), which is abundantly released in the damaged area, potently stimulates the proliferation and migration of MSCs. Recent evidence indicates that tissue in...

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Detalles Bibliográficos
Autores principales: Grigorieva, Olga, Arbatskiy, Mikhail, Novoseletskaya, Ekaterina, Dyachkova, Uliana, Ishkin, Alexander, Kalinina, Natalia, Efimenko, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533296/
https://www.ncbi.nlm.nih.gov/pubmed/34680406
http://dx.doi.org/10.3390/biomedicines9101290