Cargando…

Platelet-Derived Growth Factor Induces SASP-Associated Gene Expression in Human Multipotent Mesenchymal Stromal Cells but Does Not Promote Cell Senescence

Activation of multipotent mesenchymal stromal cells (MSCs) is a central part of tissue response to damage. Platelet-derived growth factor (PDGF-BB), which is abundantly released in the damaged area, potently stimulates the proliferation and migration of MSCs. Recent evidence indicates that tissue in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grigorieva, Olga, Arbatskiy, Mikhail, Novoseletskaya, Ekaterina, Dyachkova, Uliana, Ishkin, Alexander, Kalinina, Natalia, Efimenko, Anastasia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533296/ https://www.ncbi.nlm.nih.gov/pubmed/34680406 http://dx.doi.org/10.3390/biomedicines9101290

Ejemplares similares

Novel Potential Markers of Myofibroblast Differentiation Revealed by Single-Cell RNA Sequencing Analysis of Mesenchymal Stromal Cells in Profibrotic and Adipogenic Conditions
por: Grigorieva, Olga, et al.
Publicado: (2023)

Mesenchymal stromal cells facilitate resolution of pulmonary fibrosis by miR-29c and miR-129 intercellular transfer
por: Nataliya, Basalova, et al.
Publicado: (2023)

Mesenchymal Stromal Cell-Produced Components of Extracellular Matrix Potentiate Multipotent Stem Cell Response to Differentiation Stimuli
por: Novoseletskaya, Ekaterina, et al.
Publicado: (2020)

Secretome of Mesenchymal Stromal Cells Prevents Myofibroblasts Differentiation by Transferring Fibrosis-Associated microRNAs within Extracellular Vesicles
por: Basalova, Nataliya, et al.
Publicado: (2020)

Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo
por: Voynova, Elizaveta, et al.
Publicado: (2022)

Corrigendum: Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo
por: Voynova, Elizaveta, et al.
Publicado: (2023)

Extracellular matrix-induced signaling pathways in mesenchymal stem/stromal cells
por: Novoseletskaya, Ekaterina Sergeevna, et al.
Publicado: (2023)

Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension
por: Chechekhin, Vadim, et al.
Publicado: (2023)

Conditioned Medium from Human Mesenchymal Stromal Cells: Towards the Clinical Translation
por: Sagaradze, Georgy, et al.
Publicado: (2019)

Functional Heterogeneity of Protein Kinase A Activation in Multipotent Stromal Cells
por: Tyurin-Kuzmin, Pyotr A., et al.
Publicado: (2020)

SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells
por: Valenzuela, Claudio A., et al.
Publicado: (2019)

Secretome of Multipotent Mesenchymal Stromal Cells as a Promising Treatment and for Rehabilitation of Patients with the Novel Coronaviral Infection
por: Efimenko, A. Yu., et al.
Publicado: (2021)

Dissecting cellular senescence and SASP in Drosophila
por: Ito, Takao, et al.
Publicado: (2016)

Senescence and the SASP: many therapeutic avenues
por: Birch, Jodie, et al.
Publicado: (2020)

Decreased Insulin Sensitivity in Telomerase-Immortalized Mesenchymal Stem Cells Affects Efficacy and Outcome of Adipogenic Differentiation in vitro
por: Kulebyakin, Konstantin, et al.
Publicado: (2021)

Regulation of Immunity via Multipotent Mesenchymal Stromal Cells
por: Rubtsov, Y. P., et al.
Publicado: (2012)

Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti‐tumour properties
por: Alessio, Nicola, et al.
Publicado: (2023)

“Social Life” of Senescent Cells: What Is SASP and Why Study It?
por: Borodkina, A. V., et al.
Publicado: (2018)

Senescence utilises inflammatory caspases to drive SASP
por: Wiggins, Kimberley A., et al.
Publicado: (2019)

Senescence and Cancer: Role of Nitric Oxide (NO) in SASP
por: Mabrouk, Nesrine, et al.
Publicado: (2020)

Biliary Epithelial Senescence in Liver Disease: There Will Be SASP
por: Meadows, Vik, et al.
Publicado: (2021)

Characterization of secretomes provides evidence for adipose-derived mesenchymal stromal cells subtypes
por: Kalinina, Natalia, et al.
Publicado: (2015)

Whole Chromosome Instability induces senescence and promotes SASP
por: Andriani, Grasiella Angelina, et al.
Publicado: (2016)

Scalable Production of Equine Platelet Lysate for Multipotent Mesenchymal Stromal Cell Culture
por: Hagen, A., et al.
Publicado: (2021)

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
por: Takahashi, Akiko, et al.
Publicado: (2018)

The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells
por: Alessio, Nicola, et al.
Publicado: (2019)

Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning
por: Efimenko, Anastasia, et al.
Publicado: (2011)

A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
por: Sagaradze, Georgy, et al.
Publicado: (2019)

Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue
por: Ikegami, Kuniko, et al.
Publicado: (2023)

Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid Oxidation
por: Giuliani, Angelica, et al.
Publicado: (2023)

Proteomic Profiling of the Human Fetal Multipotent Mesenchymal Stromal Cells Secretome
por: Lobov, Arseniy A., et al.
Publicado: (2020)

Spermidine Retarded the Senescence of Multipotent Mesenchymal Stromal Cells In Vitro and In Vivo through SIRT3-Mediated Antioxidation
por: Huang, Hua, et al.
Publicado: (2023)

Evaluation of Peripheral Blood and Cord Blood Platelet Lysates in Isolation and Expansion of Multipotent Mesenchymal Stromal Cells
por: Christou, Ioanna, et al.
Publicado: (2018)

Sensitive Detection and Monitoring of Senescence-Associated Secretory Phenotype by SASP-RAP Assay
por: Gu, Liubao, et al.
Publicado: (2012)

ROCK inhibition modulates the senescence‐associated secretory phenotype (SASP) in oral keratinocytes
por: Niklander, Sven, et al.
Publicado: (2020)

The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?
por: Ohtani, Naoko
Publicado: (2022)

Apoptotic stress causes mtDNA release during senescence and drives the SASP
por: Victorelli, Stella, et al.
Publicado: (2023)

Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

DASS/SASP Workshop
por: Iqbal, M J, et al.
Publicado: (1986)

Metformin mitigates SASP secretion and LPS-triggered hyper-inflammation in Doxorubicin-induced senescent endothelial cells
por: Abdelgawad, Ibrahim Y., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_72rc2a92hf6fkvbj7jr0plsb1e