A Gadolinium DO3A Amide m-Phenyl Boronic Acid MRI Probe for Targeted Imaging of Sialated Solid Tumors

We developed a new probe, Gd-DO3A-Am-PBA, for imaging tumors. Our results showed active targeting of Gd-DO3A-Am-PBA to sialic acid (SA) moieties, with increased cellular labeling in vitro and enhanced tumor accumulation and retention in vivo, compared to the commercial Gadovist. The effectiveness of...

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Detalles Bibliográficos
Autores principales: Rajan, Christu, Seema, Jaya, Chen, Yu-Wen, Chen, Tsai-Chen, Lin, Ming-Huang, Lin, Chia-Huei, Hwang, Dennis Wen-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533322/
https://www.ncbi.nlm.nih.gov/pubmed/34680576
http://dx.doi.org/10.3390/biomedicines9101459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533322/
https://www.ncbi.nlm.nih.gov/pubmed/34680576
http://dx.doi.org/10.3390/biomedicines9101459

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