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The Capacity of APOB-Depleted Plasma in Inducing ATP-Binding Cassette A1/G1-Mediated Macrophage Cholesterol Efflux—But Not Gut Microbial-Derived Metabolites—Is Independently Associated with Mortality in Patients with ST-Segment Elevation Myocardial Infarction

Impaired HDL-mediated macrophage cholesterol efflux and higher circulating concentrations of trimethylamine N-oxide (TMAO) levels are independent risk factors for cardiovascular mortality. The TMAO precursors, γ-butyrobetaine (γBB) and Trimethyllysine (TML), have also been recently associated with c...

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Detalles Bibliográficos
Autores principales: Canyelles, Marina, García-Osuna, Álvaro, Junza, Alexandra, Yanes, Oscar, Puig, Núria, Ordóñez-Llanos, Jordi, Sionis, Alessandro, Sans-Roselló, Jordi, Alquézar-Arbé, Aitor, Santos, David, Rotllan, Noemi, Julve, Josep, Tondo, Mireia, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533386/
https://www.ncbi.nlm.nih.gov/pubmed/34680453
http://dx.doi.org/10.3390/biomedicines9101336