GYY4137 Regulates Extracellular Matrix Turnover in the Diabetic Kidney by Modulating Retinoid X Receptor Signaling

Diabetic kidney is associated with an accumulation of extracellular matrix (ECM) leading to renal fibrosis. Dysregulation of retinoic acid metabolism involving retinoic acid receptors (RARs) and retinoid X receptors (RXRs) has been shown to play a crucial role in diabetic nephropathy (DN). Furthermo...

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Detalles Bibliográficos
Autores principales: Juin, Subir Kumar, Pushpakumar, Sathnur, Sen, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533431/
https://www.ncbi.nlm.nih.gov/pubmed/34680110
http://dx.doi.org/10.3390/biom11101477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533431/
https://www.ncbi.nlm.nih.gov/pubmed/34680110
http://dx.doi.org/10.3390/biom11101477

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