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DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein
Glycation of α-synuclein (αSyn), as occurs with aging, has been linked to the progression of Parkinson’s disease (PD) through the promotion of advanced glycation end-products and the formation of toxic oligomers that cannot be properly cleared from neurons. DJ-1, an antioxidative protein that plays...
Autores principales: | Atieh, Tamr B., Roth, Jonathan, Yang, Xue, Hoop, Cody L., Baum, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533443/ https://www.ncbi.nlm.nih.gov/pubmed/34680099 http://dx.doi.org/10.3390/biom11101466 |
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