Quercetin Completely Ameliorates Hypoxia–Reoxygenation-Induced Pathophysiology Severity in NY1DD Transgenic Sickle Mice: Intrinsic Mild Steady State Pathophysiology of the Disease in NY1DD Is Also Reversed

The vaso-occlusive crisis (VOC) is a major complication of sickle cell disease (SCD); thus, strategies to ameliorate vaso-occlusive episodes are greatly needed. We evaluated the therapeutic benefits of quercetin in a SCD transgenic sickle mouse model. This disease model exhibited very mild disease p...

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Detalles Bibliográficos
Autores principales: Thangaswamy, Sangeetha, Branch, Craig A., Ambadipudi, Kamalakar, Acharya, Seetharama A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533533/
https://www.ncbi.nlm.nih.gov/pubmed/34680105
http://dx.doi.org/10.3390/biom11101473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533533/
https://www.ncbi.nlm.nih.gov/pubmed/34680105
http://dx.doi.org/10.3390/biom11101473

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