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Airway Bacteria Quantification Using Polymerase Chain Reaction Combined with Neutrophil and Eosinophil Counts Identifies Distinct COPD Endotypes

Background: Chronic obstructive pulmonary disease (COPD) inflammatory endotypes are associated with different airway microbiomes. We used quantitative polymerase chain reaction (qPCR) analysis of sputum samples to establish the bacterial load upper limit in healthy controls; these values determined...

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Detalles Bibliográficos
Autores principales: Beech, Augusta, Lea, Simon, Li, Jian, Jackson, Natalie, Mulvanny, Alex, Singh, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533560/
https://www.ncbi.nlm.nih.gov/pubmed/34680454
http://dx.doi.org/10.3390/biomedicines9101337